Concepedia

CD16 promotes Escherichia coli sepsis through an FcRγ inhibitory pathway that prevents phagocytosis and facilitates inflammation

Fabiano Pinheiro da Silva, Meryem Aloulou, David Skurnik, Marc Benhamou, Antoine Andremont, Irineu Tadeu Velasco, Murilo Chiamolera, J. Sjef Verbeek, Pierre Launay, Renato C. Monteiro

Nature Medicine · 2007 · 138 citations · 24 references

DOI

Concepts

References

24

FcR γ chain deletion results in pleiotrophic effector cell defects

Toshiyuki Takai, Min Li, Diana L. Sylvestre et al. · Cell · 1994 · 968 citations

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A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages.

Nobukazu Araki, M.T. Johnson, Joel A. Swanson · The Journal of Cell Biology · 1996 · 960 citations · Full text

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Augmented humoral and anaphylactic responses in FcγRII-deficient mice

Toshiyuki Takai, Masao Ono, Masaki Hikida et al. · Nature · 1996 · 828 citations

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Cutting Edge: Inhibition of TLR and FcR Responses in Macrophages by Triggering Receptor Expressed on Myeloid Cells (TREM)-2 and DAP12

Jessica A. Hamerman, Jessica R. Jarjoura, Mary Beth Humphrey et al. · The Journal of Immunology · 2006 · 457 citations · Full text

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Impaired IgG-Dependent Anaphylaxis and Arthus Reaction in FcγRIII (CD16) Deficient Mice

Wouter L. W. Hazenbos, J. Engelbert Gessner, Frans M.A. Hofhuis et al. · Immunity · 1996 · 448 citations · Full text

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