Concepedia

Restoration Of Glutamine Synthetase Activity, Nitric Oxide Levels And Amelioration Of Oxidative Stress By Propolis In Kainic Acid Mediated Excitotoxicity

M. Swamy, W Norlina, D Suhaili, K. N. S. Sirajudeen, Zulkarnain Mustapha, Chandran Govindasamy

African Journal of Traditional Complementary and Alternative Medicines · 2014 · 18 citations · 35 references

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Abstract

This study clearly demonstrated the restoration of GS activity, NO levels and decreased oxidative stress by propolis in kainic acid mediated excitotoxicity. Hence the propolis can be a possible potential candidate (protective agent) against excitotoxicity and neurodegenerative disorders.

References

35

Method for the measurement of antioxidant activity in human fluids

D Koraćević · Journal of Clinical Pathology · 2001 · 1.9K citations · Full text

Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway

Cathy Tournier, Patricia Hess, Derek Yang et al. · Science · 2000 · 1.7K citations

Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B.

Kasthuri Natarajan, Sandeep Singh, Terrence R. Burke et al. · Proceedings of the National Academy of Sciences · 1996 · 1.1K citations · Full text

, , +18

Dopamine Oxidation Alters Mitochondrial Respiration and Induces Permeability Transition in Brain Mitochondria

Sarah Berman, Teresa G. Hastings · Journal of Neurochemistry · 1999 · 659 citations

Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation

M. Maalouf, Patrick G. Sullivan, Lydia J. Davis et al. · Neuroscience · 2007 · 461 citations · Full text

, , +10