Concepedia

Involvement of Extracellular Signal-Regulated Kinase Activation in Human Osteosarcoma Cell Resistance to the Histone Deacetylase Inhibitor FK228 [(1 S,4 S,7 Z,10 S,16 E,21 R)-7-Ethylidene-4,21-bis(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone]

Hiroshi Matsubara, Motonobu Watanabe, Tsuyoshi Imai, Yoshihiro Yui, Yasuhiro Mizushima, Yoshimi Hiraumi, Yuri Kamitsuji, Ken-ichiro Watanabe, Koichi Nishijo, Junya Toguchida,

Journal of Pharmacology and Experimental Therapeutics · 2008 · 22 citations · 34 references

DOI

Concepts

References

34

The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival

Xiantao Wang, Jennifer L. Martindale, Nikki J. Holbrook · Biochemical Journal · 1998 · 739 citations · Full text

, , +15

The caspase-8 inhibitor FLIP promotes activation of NF-κB and Erk signaling pathways

Takao Kataoka, Ralph C. Budd, Nils Holler et al. · Current Biology · 2000 · 552 citations · Full text

, , +13

Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms.

Victor Sandor, Susan Bakke, Robert W. Robey et al. · PubMed · 2002 · 510 citations

, , +12

Modulation of p53, ErbB1, ErbB2, and Raf-1 Expression in Lung Cancer Cells by Depsipeptide FR901228

Xiaomin Yu · JNCI Journal of the National Cancer Institute · 2002 · 359 citations · Full text

, , +17

Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute drug screen.

J S Lee, K Paull, Curtis Hose et al. · Molecular Pharmacology · 1994 · 340 citations

, , +11