cDNA Cloning of a New Low-Density Lipoprotein Receptor-Related Protein and Mapping of Its Gene (LRP3) to Chromosome Bands 19q12–q13.2

A simple method for displaying the hydropathic character of a protein

Jack Kyte, Russell F. Doolittle · Journal of Molecular Biology · 1982 · 23.1K citations

Life Sciences, Biochemistry, Molecular Biology +12

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

Tokuo Yamamoto, Christopher G. Davis, Michael S. Brown et al. · Cell · 1984 · 1.4K citations

Life Sciences, Biochemistry, Molecular Biology +11

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.

Wei J. Chen, J L Goldstein, Mark S. Brown · Journal of Biological Chemistry · 1990 · 944 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins.

Shun Ishibashi, Joachim Herz, N Maeda et al. · Proceedings of the National Academy of Sciences · 1994 · 422 citations

Life Sciences, Biochemistry, Molecular Biology +12

Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptor.

Philip K. Frykman, Michael S. Brown, Tokuo Yamamoto et al. · Proceedings of the National Academy of Sciences · 1995 · 255 citations

Life Sciences, Biochemistry, Molecular Genetics +16