Transcription · 2010 · 20 citations · 19 references
Life SciencesMolecular BiologyMolecular GeneticsGene ExpressionTranscriptionTranscriptional RegulationCore Promoter ElementsCpg IslandsPromoter RegulationRna TranscriptionTelomere BiologyTranscription In EukaryotesCpg Island Gene RegulationCpg Island Promoter AssociationCpg Island PromotersPromotersTelomere FunctionTelomeric Dna Repeat SequencesTelomeric RepeatsTelomeric Rna (Terra)
We recently identified CpG island promoters driving transcription of human telomeric repeat-containing RNA (TERRA). This discovery has shaped a new concept in telomere biology, where TERRA promoters and downstream telomeric sequences constitute autonomous genic units.
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