Transition of Cationic Dipeptide Nanotubes into Vesicles and Oligonucleotide Delivery

Abstract

Password?—Vesicle! A cationic dipeptide can self-assemble into nanotubes at physiological pH values. Such self-assembled cationic dipeptide nanotubes (CDPNTs) are able to convert into vesicles spontaneously upon dispersion dilution and thus carry single-stranded DNA into HeLa cells across the biomembrane (see picture). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z603387_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.