Angewandte Chemie International Edition · 2004 · 1.1K citations · 23 references
Life SciencesBioengineeringBiotechnologyDrug DeliveryNanomaterialsNanotechnologyDna NanotechnologyGene Delivery SystemsNanomedicineNanotubesNucleic Acid DeliveryPlasmid Dna DeliveryDna NanocarriersFunctionalized Carbon NanomaterialsGene Delivery BiomaterialsGene Delivery NanocarriersGene Delivery NanomaterialsNonviral Delivery SystemsNonviral Gene Delivery VectorsPlasmid-based Gene Delivery
Genetic vaccination and gene therapy research could benefit from the application of carbon nanotubes. Functionalized, positively charged, water-soluble carbon nanotubes are able to penetrate into cells (see figure) and can transport plasmid DNA by formation of noncovalent DNA–nanotube complexes. Such nanotubes can be used as novel nonviral delivery systems for gene transfer.
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DNA-assisted dispersion and separation of carbon nanotubes
Ming Zheng, Anand Jagota, E. D. Semke et al. · Nature Materials · 2003 · 2.7K citations
Structure-Based Carbon Nanotube Sorting by Sequence-Dependent DNA Assembly
Ming Zheng, Anand Jagota, Michael S. Strano et al. · Science · 2003 · 1.6K citations