A Role for Leukocyte-Derived IL-1RA in DC Homeostasis Revealed by Increased Susceptibility of IL-1RA-Deficient Mice to Cutaneous Leishmaniasis

Biologic basis for interleukin-1 in disease

CA Dinarello · Blood · 1996 · 4.4K citations · Full text

Life Sciences, Cell Biology, Immunology +12

Interleukin-1 Type II Receptor: A Decoy Target for IL-1 That Is Regulated by IL-4

Francesco Colotta, Fabio Re, Marta Muzio et al. · Science · 1993 · 982 citations

Life Sciences, Immunology, Pathology +15

Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade

Virginia Pascual, Florence Allantaz, Edsel Arce et al. · The Journal of Experimental Medicine · 2005 · 917 citations · Full text

Life Sciences, Immunology, Pathobiology +17

Development of Chronic Inflammatory Arthropathy Resembling Rheumatoid Arthritis in Interleukin 1 Receptor Antagonist–Deficient Mice

Reiko Horai, Shinobu Saijo, Hidetoshi Tanioka et al. · The Journal of Experimental Medicine · 2000 · 756 citations · Full text

Medicine, Immunology, Pathology +17

Production of Mice Deficient in Genes for Interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 Receptor Antagonist Shows that IL-1β Is Crucial in Turpentine-induced Fever Development and Glucocorticoid Secretion

Reiko Horai, Masahide Asano, Katsuko Sudo et al. · The Journal of Experimental Medicine · 1998 · 615 citations · Full text

Life Sciences, Immunology, Physiology +16