The synthesis of modified achiral internucleoside linkages: -NHCH2CH2- linked oligonucleosides

Readily accessible 12-I-5 oxidant for the conversion of primary and secondary alcohols to aldehydes and ketones

D. B. DESS, J. C. Martin · The Journal of Organic Chemistry · 1983 · 3.1K citations

Chemical Measurement, Engineering, Aldehyde Dehydrogenase +15

Anti-cancer Drug Design

M SISSAOUI · Archives of Clinical Microbiology · 2018 · 1.4K citations

Drug Design, Medicine, Pharmacology +8

Building blocks for oligonucleotide analogs with dimethylene sulfide, sulfoxide, and sulfone groups replacing phosphodiester linkages

Zhen Huang, Klaus Schneider, Steven A. Benner · The Journal of Organic Chemistry · 1991 · 104 citations

Building Blocks, Bioorganic Chemistry, Engineering +17

Oligonucleosides: synthesis of a novel methylhydroxylamine-linked nucleoside dimer and its incorporation into antisense sequences

Jean‐Jacques Vasseur, Françoise Debart, Yogesh S. Sanghvi et al. · Journal of the American Chemical Society · 1992 · 89 citations

Combinatorial Chemistry, Molecular Sciences, Bioorganic Chemistry +15

Deoxyoligonucleotide analogs based on formacetal linkages

Mark Matteucci · Tetrahedron Letters · 1990 · 75 citations

Natural Sciences, Oligonucleotide, Deoxyoligonucleotide Analogs +2