Antitumor platinum(IV) derivatives of oxaliplatin with axial valproato ligands

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

Martin Göttlicher · The EMBO Journal · 2001 · 1.9K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

FDA Approval Summary: Vorinostat for Treatment of Advanced Primary Cutaneous T-Cell Lymphoma

Bhupinder Mann, John R. Johnson, Martin H. Cohen et al. · The Oncologist · 2007 · 1.4K citations · Full text

Medicine, Oncology, Pharmacotherapy +14

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA–PEG nanoparticles

Shanta Dhar, Frank Gu, Róbert Langer et al. · Proceedings of the National Academy of Sciences · 2008 · 990 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +14

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases.

Ryohei Furumai, Akihisa Matsuyama, Nobuyuki Kobashi et al. · PubMed · 2002 · 744 citations

Life Sciences, Medicinal Chemistry, Pharmacology +13

Targeted Single-Wall Carbon Nanotube-Mediated Pt(IV) Prodrug Delivery Using Folate as a Homing Device

Shanta Dhar, Zhuang Liu, Jürgen Thomale et al. · Journal of the American Chemical Society · 2008 · 695 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17