Concepedia

p62 (SQSTM1) and cyclic AMP phosphodiesterase-4A4 (PDE4A4) locate to a novel, reversible protein aggregate with links to autophagy and proteasome degradation pathways

Christian Frank, Diana F. Anthony, Suryakiran Vadrevu, Tracy Riddell, Jonathan P. Day, Ruth McLeod, David R. Adams, George S. Baillie, Miles D. Houslay

Cellular Signalling · 2010 · 44 citations · 87 references

DOI

Concepts

References

87

p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy

Serhiy Pankiv, Terje Høyvarde Clausen, Trond Lamark et al. · Journal of Biological Chemistry · 2007 · 4.5K citations · Full text

, , +17

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

Tetsu Akiyama, Junko Ishida, Shizue Nakagawa et al. · Journal of Biological Chemistry · 1987 · 3.7K citations · Full text

, , +15

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Geir Bjørkøy, Trond Lamark, Andreas Brech et al. · The Journal of Cell Biology · 2005 · 3.3K citations · Full text

, , +15

Aggresomes: A Cellular Response to Misfolded Proteins

Jennifer Johnston, Cristina L. Ward, Ron R. Kopito · The Journal of Cell Biology · 1998 · 2.2K citations · Full text

, , +17

Identification of a Primary Target of Thalidomide Teratogenicity

Takumi Ito, Hideki Ando, Takayuki Suzuki et al. · Science · 2010 · 2.1K citations

, , +13