Ligands for peroxisome proliferator-activated receptor gamma have potent antitumor effect against human renal cell carcinoma

PPAR-γ agonists inhibit production of monocyte inflammatory cytokines

Chengyu Jiang, Adrian T. Ting, Brian Seed · Nature · 1998 · 2.9K citations

Inflammation, Cytokine, Anti-inflammatory +8

PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL

Peter Tontonoz, László Nagy, Jacqueline G. Alvarez et al. · Cell · 1998 · 1.8K citations · Full text

Inflammation, Oxysterol, Lipid Peroxidation +8

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

Steven A. Kliewer, Kazuhiko Umesono, Daniel J. Noonan et al. · Nature · 1992 · 1.7K citations · Full text

Signal Transduction, Heterodimer Formation, Biochemistry +9

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

Jin Jiang, Gary Struhl · Nature · 1998 · 1.7K citations

Signal Transduction, Developmental Biology, Signaling Pathway +5

Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo.

Tetsuya Kubota, Kozo Koshizuka, Elizabeth A. Williamson et al. · PubMed · 1998 · 588 citations

Tumor Biology, Urology, Medicine +13