Concepedia

Global brain hypoperfusion and oxygenation in amnestic mild cognitive impairment

Jie Liu, Yongsheng Zhu, Muhammad Ayaz Khan, Estee Brunk, Kristin Martin‐Cook, Myron Weiner, C. Munro Cullum, Hanzhang Lu, Benjamin D. Levine, Ramon Diaz‐Arrastia,

Alzheimer s & Dementia · 2013 · 76 citations · 40 references

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Abstract

Global brain hypoperfusion, oxygen hypometabolism, and neurovascular decoupling observed in aMCI suggest that changes in cerebral hemodynamics occur early at a prodromal stage of Alzheimer's disease, which can be assessed using low-cost and bedside-available CDUS and NIRS technology.

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