Kinetic resolution of (±)-2,3-dihydro-3-methyl-4H-1,4-benzoxazines with (S)-naproxen

synthesis and antibacterial activities of optically active ofloxacin and its fluoromethyl derivative.

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L-prolinyl Chloride.the, Organic Chemistry, Antimicrobial Chemotherapy +21

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Lester A. Mitscher, Padam N. Sharma, Daniel T. W. Chu et al. · Journal of Medicinal Chemistry · 1987 · 100 citations · Full text

Bioorganic Chemistry, Optical Antipodes, Antibiotic Adjuvant +22

Synthesis of a key intermediate of levofloxacin via enantioselective hydrogenation catalyzed by iridium(I) complexes

Koji Satoh, Minako Inenaga, Kazuaki Kanai · Tetrahedron Asymmetry · 1998 · 64 citations

Enantioselective Synthesis, Key Intermediate, Engineering +7

The disposition of venlafaxine enantiomers in dogs, rats, and humans receiving venlafaxine

C. Paul Wang, Stanley R. Howell, JoAnn Scatina et al. · Chirality · 1992 · 59 citations

Asymmetric reduction of 7,8‐difluoro‐3‐methyl‐2<i>H</i>‐1,4‐benzoxazine. Synthesis of a key intermediate of (<i>S</i>)‐(‐)‐ofloxacin (DR‐3355)

Shohgo Atarashi, H. TSURUMI, Toshihiro Fujiwara et al. · Journal of Heterocyclic Chemistry · 1991 · 55 citations