Poly(I:C) combined with multi-epitope protein vaccine completely protects against virulent foot-and-mouth disease virus challenge in pigs

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Lena Alexopoulou, Agnieszka Czopik Holt, Ruslan Medzhitov et al. · Nature · 2001 · 6.1K citations

Life Sciences, Immunology, Molecular Biology +14

Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant

M. Paula Longhi, Christine Trumpfheller, Juliana Idoyaga et al. · The Journal of Experimental Medicine · 2009 · 646 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Differentiation of infection from vaccination in foot-and-mouth disease by the detection of antibodies to the non-structural proteins 3D, 3AB and 3ABC in ELISA using antigens expressed in baculovirus

K. J. Sørensen, K. G. Madsen, E. S. Madsen et al. · Archives of Virology · 1998 · 273 citations

Life Sciences, Immunology, Infectious Diseases +11

A large-scale evaluation of peptide vaccines against foot-and-mouth disease: lack of solid protection in cattle and isolation of escape mutants

Oscar Taboga, Cecilia Tami, Elisa Carrillo et al. · Journal of Virology · 1997 · 232 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

Prototype Alzheimer’s Disease Vaccine Using the Immunodominant B Cell Epitope from β-Amyloid and Promiscuous T Cell Epitope Pan HLA DR-Binding Peptide

Michael G. Agadjanyan, Anahit Ghochikyan, Irina Petrushina et al. · The Journal of Immunology · 2005 · 184 citations · Full text

Life Sciences, Immunology, Pathobiology +17