Activation of integrin β1-focal adhesion kinase-RasGTP pathway plays a critical role in TGF beta1-induced podocyte injury

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

Eve J. Lowenstein, Roger J. Daly, Andreas Batzer et al. · Cell · 1992 · 1.6K citations · Full text

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

David D. Schlaepfer, Steven K. Hanks, Tony Hunter et al. · Nature · 1994 · 1.6K citations

Signal Transduction, Focal Adhesion Kinase, Ras Pathway +11

Autophosphorylation of the Focal Adhesion Kinase, ppl25^FAK, Directs SH2-Dependent Binding of pp60<i>^src</i>

Michael D. Schaller, Jeffrey D. Hildebrand, John D. Shannon et al. · Molecular and Cellular Biology · 1994 · 1.1K citations · Full text

Cell Adhesion, Molecular Biology, Cytoskeleton +19

Tyrosine Phosphorylation of Focal Adhesion Kinase at Sites in the Catalytic Domain Regulates Kinase Activity: a Role for Src Family Kinases

Mihail CALALB, Thomas R. Polte, Steven K. Hanks · Molecular and Cellular Biology · 1995 · 980 citations · Full text

Cell Adhesion, Immunology, Molecular Biology +16

Rearrangements of the Cytoskeleton and Cell Contacts Induce Process Formation during Differentiation of Conditionally Immortalized Mouse Podocyte Cell Lines

Peter Mündel, Jochen Reiser, Aimée Zúñiga et al. · Experimental Cell Research · 1997 · 879 citations

Developmental Biology, Cell Division, Cell Adhesion +8