Concepedia

Process validation and clinical evaluation of a protocol to generate gene-modified T lymphocytes for imunogene therapy for metastatic renal cell carcinoma: GMP-controlled transduction and expansion of patient's T lymphocytes using a carboxy anhydrase IX-specific scFv transgene

C. B. H. W. Lamers, Pascal van Elzakker, S.C.L. Langeveld, Stefan Sleijfer, J.W. Gratama

Cytotherapy · 2006 · 35 citations · 26 references

DOI

Concepts

References

26

Reconstitution of Cellular Immunity against Cytomegalovirus in Recipients of Allogeneic Bone Marrow by Transfer of T-Cell Clones from the Donor

Elizabeth Walter, Philip D. Greenberg, M. Jean Gilbert et al. · New England Journal of Medicine · 1995 · 1.8K citations

Adoptive Cell Transfer Therapy Following Non-Myeloablative but Lymphodepleting Chemotherapy for the Treatment of Patients With Refractory Metastatic Melanoma

Mark E. Dudley, John R. Wunderlich, James Chih‐Hsin Yang et al. · Journal of Clinical Oncology · 2005 · 1.6K citations · Full text

Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors.

Zelig Eshhar, Tova Waks, G. Gross et al. · Proceedings of the National Academy of Sciences · 1993 · 1.6K citations · Full text

, , +17

Adoptive T cell therapy using antigen-specific CD8<sup>+</sup>T cell clones for the treatment of patients with metastatic melanoma:<i>In vivo</i>persistence, migration, and antitumor effect of transferred T cells

Cassian Yee, John A. Thompson, D. Byrd et al. · Proceedings of the National Academy of Sciences · 2002 · 1.2K citations · Full text

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

Jason M. Brenchley, Nitin J. Karandikar, Michael R. Betts et al. · Blood · 2003 · 1K citations