Carbon Nanodots Featuring Efficient FRET for Real‐Time Monitoring of Drug Delivery and Two‐Photon Imaging

Jing Tang, Biao Kong, Hao Wu, Ming Xu, Yongcheng Wang, Yanli Wang, Dongyuan Zhao, Gengfeng Zheng

Advanced Materials · 2013 · 560 citations · 36 references

Concepts

Abstract

A FRET-based carbon nanodot (CDot) drug delivery platform has been developed. These CDots offer excellent biocompatibility, stable fluorescence, and efficient FRET between CDots and the attached fluorescent drug molecules, such as doxorubicin, enabling enhanced drug delivery, convenient cell imaging, and real-time monitoring of drug release. Moreover, the FRET-based two-photon imaging and drug tracking in deep tissues are also demonstrated. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

References

36