Concepedia

Key regulators in bee venom-induced apoptosis are Bcl-2 and caspase-3 in human leukemic U937 cells through downregulation of ERK and Akt

Dong‐Oh Moon, Sung Yong Park, Moon‐Soo Heo, Ki-Cheon Kim, Cheol Park, Woo Shin Ko, Yung Hyun Choi, Gi‐Young Kim

International Immunopharmacology · 2006 · 149 citations · 22 references

DOI

Concepts

References

22

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.3K citations · Full text

, , +17

Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

Zhengui Xia, Martin Dickens, Joël Raingeaud et al. · Science · 1995 · 5.3K citations

, , +16

Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

Muneesh Tewari, Long T. Quan, Karen O’Rourke et al. · Cell · 1995 · 2.4K citations · Full text

, , +15

The c‐IAP‐1 and c‐IAP‐2 proteins are direct inhibitors of specific caspases

Natalie Roy · The EMBO Journal · 1997 · 1.3K citations · Full text

, , +14

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

Scott Kennedy, Andrew J. Wagner, Suzanne D. Conzen et al. · Genes & Development · 1997 · 1.1K citations · Full text

, , +16