Neonatal Alcohol Exposure Differentially Alters Clock Gene Oscillations Within the Suprachiasmatic Nucleus, Cerebellum, and Liver of Adult Rats

Abstract

These results demonstrate alcohol exposure during the brain growth spurt alters the circadian regulation of some molecular components of the clock mechanism in the rat SCN, cerebellum, and liver. The observed alterations in the temporal configuration of essential "gears" of the molecular clockworks may play a role in the long-term effects of neonatal alcohol exposure on the regulation of circadian behavior.

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