Elevation of ceramide and activation of secretory acid sphingomyelinase in patients with acute coronary syndromes

Wei Pan, Jingjia Yu, Ruizheng Shi, Yan Lei, Tianlun Yang, Yuan‐Jian Li, Zhuohua Zhang, Guolong Yu, Yongping Bai, Edward H. Schuchman,

Coronary Artery Disease · 2014 · 81 citations · 0 references

DOI

Abstract

Serial changes in plasma ceramide and S-SMase activity were documented in patients with ACS. These findings provide an insight into the molecular mechanism of plaque destabilization.