Concepedia

Synthesis and evaluation of anticancer activity of novel andrographolide derivatives

Ponnam Devendar, Vadithe Lakshma Nayak, Dharmendra Kumar Yadav, Arigari Niranjana Kumar, Jonnala Kotesh Kumar, KVN Satya Srinivas, Balasubramanian Sridhar, Feroz Khan, Kakaraparthi Pandu Sastry, Ramakrishna Sistla

MedChemComm · 2015 · 26 citations · 32 references

DOI

Concepts

Abstract

Ceric ammonium nitrate facilitates andrographolide-3,19-<italic>O</italic>-acetal formation with alcohols. Anticancer active derivatives showed good docking scores in <italic>in silico</italic>.

References

32

Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

Cai‐Hong Yun, Titus J. Boggon, Yiqun Li et al. · Cancer Cell · 2007 · 1.1K citations · Full text

, , +6

Immunostimulant Agents from Andrographis paniculata

Anju Puri, R. K. Saxena, Rachna Saxena et al. · Journal of Natural Products · 1993 · 409 citations

Protecting Group Strategies in Organic Synthesis

Michael Schelhaas, Herbert Waldmann · Angewandte Chemie International Edition in English · 1996 · 321 citations

, , +10

Andrographolide, a potential cancer therapeutic agent isolated from <i>Andrographis paniculata</i>

Sriram Rajagopal, R. Ajaya Kumar, Dhanvanthri S. Deevi et al. · Journal of Experimental Therapeutics and Oncology · 2003 · 316 citations

Chiral acetals in asymmetric synthesis

Alexandre Alexakis, Pierre Mangeney · Tetrahedron Asymmetry · 1990 · 271 citations

, , +3