Role of Pax4 in Pdx1-VP16-mediated liver-to-endocrine pancreas transdifferentiation

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion.

Hans E. Hohmeier, Hindrik Mulder, G Chen et al. · Diabetes · 2000 · 938 citations · Full text

Life Sciences, Cell Biology, Endocrinology +14

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

Beatriz Sosa‐Pineda, Kamal Chowdhury, Miguel Torres et al. · Nature · 1997 · 798 citations

Life Sciences, Molecular Biology, Molecular Genetics +14

Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

Sarah Ferber, Amir Halkin, Hofit Cohen et al. · Nature Medicine · 2000 · 746 citations

Medicine, Endocrinology, Genetics +15

A bipotential precursor population for pancreas and liver within the embryonic endoderm

Gail Deutsch, Joonil Jung, Ming‐Hua Zheng et al. · Development · 2001 · 612 citations

Life Sciences, Biology, Developmental Biology +17

<i>In vitro</i> trans-differentiation of adult hepatic stem cells into pancreatic endocrine hormone-producing cells

Lijun Yang, Shiwu Li, Heather Hatch et al. · Proceedings of the National Academy of Sciences · 2002 · 494 citations · Full text

Life Sciences, Cell Biology, Endocrinology +17