Effect of Atorvastatin on Plasma Levels of Asymmetric Dimethylarginine in Patients with Non-Ischaemic Heart Failure

Abstract

Short-term atorvastatin treatment in non-ischaemic CHF improves endothelial function but has no effect on ADMA or the l-arginine to ADMA ratio. Our finding suggests that the observed statin-induced improvements in endothelial function are likely mediated via alternative pathways.