Concepedia

Synthesis and in vivo antimatarial activity of 12α-trifluoromethyl-hydroartemisinin

Ahmed Abouabdellah, Jean‐Pierre Bégué, Danièle Bonnet‐Delpon, Jean-Charles Gantier, Truong Thi Thanh Nga, Truong Dinh Thac

Bioorganic & Medicinal Chemistry Letters · 1996 · 42 citations · 25 references

DOI

Concepts

References

25

Synthetic methods and reactions. 141. Fluoride-induced trifluoromethylation of carbonyl compounds with trifluoromethyltrimethylsilane (TMS-CF3). A trifluoromethide equivalent

G. K. Surya Prakash, Ramesh Krishnamurti, George A. Olah · Journal of the American Chemical Society · 1989 · 529 citations

, , +4

Arteether, a new antimalarial drug: synthesis and antimalarial properties

A. BROSSI, B. Venugopalan, Lourdes Dominguez Gerpe et al. · Journal of Medicinal Chemistry · 1988 · 317 citations

, , +8

Preparation of trifluoromethyl and other perfluoroalkyl compounds with (perfluoroalkyl)trimethylsilanes

Ramesh Krishnamurti, Donald R. Bellew, G. K. Surya Prakash · The Journal of Organic Chemistry · 1991 · 273 citations

, , +5

Antimalarial activity of new water-soluble dihydroartemisinin derivatives

Lin Ai, Daniel L. Klayman, Wilbur K. Milhous · Journal of Medicinal Chemistry · 1987 · 226 citations

, , +9

Picornavirus Inhibitors: Trifluoromethyl Substitution Provides a Global Protective Effect against Hepatic Metabolism

Guy D. Diana, Patrick J. Rudewicz, Daniel C. Pevear et al. · Journal of Medicinal Chemistry · 1995 · 104 citations

, , +16