Patrick J. Rudewicz

Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases

A. S. Nagle, Agnes Biggart, C. Be et al. · Journal of Medicinal Chemistry · 2020 · 117 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +14

Picornavirus Inhibitors: Trifluoromethyl Substitution Provides a Global Protective Effect against Hepatic Metabolism

Guy D. Diana, Patrick J. Rudewicz, Daniel C. Pevear et al. · Journal of Medicinal Chemistry · 1995 · 104 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Evaluation of a Four-Channel Multiplexed Electrospray Triple Quadrupole Mass Spectrometer for the Simultaneous Validation of LC/MS/MS Methods in Four Different Preclinical Matrixes

Liyu Yang, Thierry Mann, David Little et al. · Analytical Chemistry · 2001 · 80 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +17

A Phase IB Trial of Intravenous INO-1001 Plus Oral Temozolomide in Subjects with Unresectable Stage-III or IV Melanoma

Agop Y. Bedikian, Nicholas E. Papadopoulos, Kevin B. Kim et al. · Cancer Investigation · 2009 · 69 citations

Pharmacy, Oncology, Pharmacokinetics +17

Rapid structure elucidation of catecholamine conjugates with tandem mass spectrometry

Patrick J. Rudewicz, Kenneth Straub · Analytical Chemistry · 1986 · 67 citations

Natural Sciences, Biochemistry, Chemistry +15