Concepedia

Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice

Xiaoling Xu, Steven G. Brodie, Xiao Yang, Young‐Hyuck Im, W. Tony Parks, Lin Chen, Yong‐Xing Zhou, Michael I. Weinstein, Seong‐Jin Kim, Chu‐Xia Deng

Oncogene · 2000 · 238 citations · 31 references

DOI

Concepts

References

31

<i>DPC4</i> , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1

Stephan A. Hahn, Mieke Schutte, A.T.M. Shamsul Hoque et al. · Science · 1996 · 2.3K citations

, , +17

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF‐β

Xiao Yang · The EMBO Journal · 1999 · 902 citations

, , +16

Mutations in the <i>SMAD4/DPC4</i> Gene in Juvenile Polyposis

James R. Howe, Stina Roth, John C. Ringold et al. · Science · 1998 · 897 citations

, , +17

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

Matthew L. Fero, Erin Randel, Kay E. Gurley et al. · Nature · 1998 · 788 citations · Full text

, , +14

Smad3 Mutant Mice Develop Metastatic Colorectal Cancer

Yuan Zhu, James A. Richardson, Luis F. Parada et al. · Cell · 1998 · 672 citations · Full text

, , +10