Down regulation of serotonin-S2 receptor sites in rat brain by chronic treatment with the serotonin-S2 antagonists: ritanserin and setoperone

Multiple Serotonin Receptors: Differential Binding of [3H]5-Hydroxytryptamine, [3H]Lysergic Acid Diethylamide and [3H]Spiroperidol

Stephen J. Peroutka, Solomon H. Snyder · Molecular Pharmacology · 1979 · 1.4K citations

Medicine, Neuroscience, Pharmacology +15

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

J E Leysen, C. J. E. Niemegeers, Jan M. Van Nueten et al. · Molecular Pharmacology · 1982 · 1.1K citations

Medicine, Medicinal Chemistry, Pharmacology +17

Development of β-adrenergic receptor subsensitivity by antidepressants

Shailesh P. Banerjee, Lily S. Kung, Stephen J. Riggi et al. · Nature · 1977 · 723 citations

Medicine, Pharmacology, Pharmacotherapy +12

Serotonergic component of neuroleptic receptors

Josée E. Leysen, C. J. E. Niemegeers, J.P. Tollenaere et al. · Nature · 1978 · 626 citations

Life Sciences, Neuroscience, Pharmacology +14

Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist.

J.E. Leysen, W Gommeren, Paul Van Gompel et al. · Molecular Pharmacology · 1985 · 453 citations

Medicine, Medicinal Chemistry, Pharmacology +13