Concepedia

Characterizing the mechanism of thiazolidinedione-induced hepatotoxicity: An in vitro model in mitochondria

Dan Hu, Chunqi Wu, Zejun Li, Yue Liu, Xing Fan, Quanjun Wang

Toxicology and Applied Pharmacology · 2015 · 56 citations · 24 references

DOI

Concepts

References

24

The Structure−Activity Relationship between Peroxisome Proliferator-Activated Receptor γ Agonism and the Antihyperglycemic Activity of Thiazolidinediones

Timothy M. Willson, Jeffery E. Cobb, David J. Cowan et al. · Journal of Medicinal Chemistry · 1996 · 639 citations · Full text

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Two Cases of Severe Clinical and Histologic Hepatotoxicity Associated with Troglitazone

Norman Gitlin · Annals of Internal Medicine · 1998 · 230 citations

, , +14

Mitochondrial Network Determines Intracellular ROS Dynamics and Sensitivity to Oxidative Stress through Switching Inter-Mitochondrial Messengers

Junseong Park, Jungsul Lee, Chulhee Choi · PLoS ONE · 2011 · 229 citations · Full text

, , +17

The mitochondrial DNA polymerase as a target of oxidative damage

Maria A Graziewicz · Nucleic Acids Research · 2002 · 186 citations

, , +17

The role of ROS in microcystin-LR-induced hepatocyte apoptosis and liver injury in mice

Dan Weng, Yan Lu, Yinna Wei et al. · Toxicology · 2006 · 186 citations

, , +14