An efficient algorithm for identifying matches with errors in multiple long molecular sequences

A general method applicable to the search for similarities in the amino acid sequence of two proteins

Saul B. Needleman, Christian D. Wunsch · Journal of Molecular Biology · 1970 · 11.5K citations

Life Sciences, Biochemistry, Bioinformatics +13

Improved tools for biological sequence comparison.

William R. Pearson, David J. Lipman · Proceedings of the National Academy of Sciences · 1988 · 11.3K citations · Full text

Life Sciences, Bioinformatics, Biology +15

A workbench for multiple alignment construction and analysis

Gregory D. Schuler, Stephen F. Altschul, David J. Lipman · Proteins Structure Function and Bioinformatics · 1991 · 993 citations

Life Sciences, Bioinformatics, Biology +13

An expectation maximization (EM) algorithm for the identification and characterization of common sites in unaligned biopolymer sequences

Charles E. Lawrence, Andrew Reilly · Proteins Structure Function and Bioinformatics · 1990 · 544 citations

Life Sciences, Bioinformatics, Molecular Biology +13

Predictive motifs derived from cytosine methyltransferases

János Pósfai, Ashok S. Bhagwat, György Pósfai et al. · Nucleic Acids Research · 1989 · 493 citations · Full text

Life Sciences, Genetics, Molecular Biology +14