Improved Brain Uptake and Pharmacological Activity Profile of Morphine-6-Glucuronide Using a Peptide Vector-Mediated Strategy

Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite.

Dennis Paúl, Kelly M. Standifer, Charles E. Inturrisi et al. · Journal of Pharmacology and Experimental Therapeutics · 1989 · 395 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Morphine-6-glucuronide: Analgesic effects and receptor binding profile in rats

Frances V. Abbott, Roberta M. Palmour · Life Sciences · 1988 · 192 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Antinociceptive and ventilatory effects of the morphine metabolites: morphine-6-glucuronide and morphine-3-glucuronide

Qian-Ling Gong, Thomas Hedner, Jan Hedner et al. · European Journal of Pharmacology · 1991 · 178 citations

Medicine, Anesthesiology, Pharmacology +12

Role of mu and delta receptors in the supraspinal and spinal analgesic effects of [D-Pen2, D-Pen5] enkephalin in the mouse

F. Porreca, Julius S. Heyman, Henry I. Mosberg et al. · Pain · 1988 · 166 citations

Medicine, Neuroscience, Pharmacology +17

Further evidence that morphine-6 beta-glucuronide is a more potent opioid agonist than morphine.

Bernard Francès, Robert Gout, Bernard Monsarrat et al. · Journal of Pharmacology and Experimental Therapeutics · 1992 · 161 citations

Medicine, Pharmacology, Neuropharmacology +16