Solid-phase synthesis of α-hydroxy phosphonates and hydroxystatine amides. Transition-state isosteres derived from resin-bound amino acid aldehydes

Potent, Low-Molecular-Weight Non-Peptide Inhibitors of Malarial Aspartyl Protease Plasmepsin II

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Life Sciences, Biochemistry, Medicinal Chemistry +17

Versatile Approach To Encoding Combinatorial Organic Syntheses Using Chemically Robust Secondary Amine Tags

Zhi‐Jie Ni, Derek Maclean, Christopher P. Holmes et al. · Journal of Medicinal Chemistry · 1996 · 106 citations

Pharmacy, Chemical Engineering, Chemistry +13

The rapid identification of HIV protease inhibitors through the synthesis and screening of defined peptide mixtures

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Pharmacy, Biochemistry, Medicinal Chemistry +16

Synthetic chemical diversity: solid phase synthesis of libraries of C2 symmetric inhibitors of HIV protease containing diamino diol and diamino alcohol cores

Gary T. Wang, Sam Li, Norman E. Wideburg et al. · Journal of Medicinal Chemistry · 1995 · 78 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Identification of potent inhibitors of Plasmodium falciparum plasmepsin II from an encoded statine combinatorial library

Carolyn DiIanni Carroll, Hitesh D. Patel, Theodore Johnson et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16