Concepedia

Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain

Shanshan Feng, Yonghui Yang, Yide Mei, Li Ma, De-e Zhu, Naseruddin Höti, Mark Castanares, Mian Wu

Cellular Signalling · 2007 · 442 citations · 20 references

DOI

Concepts

References

20

Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule

Nils Holler, Rossana Zaru, Olivier Micheau et al. · Nature Immunology · 2000 · 1.9K citations

, , +14

The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal

Michelle A. Kelliher, Stefan Grimm, Yasumasa Ishida et al. · Immunity · 1998 · 1.1K citations · Full text

, , +14

RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation

Etienne Meylan, Kim Burns, Kay Hofmann et al. · Nature Immunology · 2004 · 837 citations · Full text

, , +14

Cleavage of the death domain kinase RIP by Caspase-8 prompts TNF-induced apoptosis

Ying Lin, Anne Devin, Yolanda Rodríguez et al. · Genes & Development · 1999 · 829 citations · Full text

, , +16

Kinase RIP3 Is Dispensable for Normal NF-κBs, Signaling by the B-Cell and T-Cell Receptors, Tumor Necrosis Factor Receptor 1, and Toll-Like Receptors 2 and 4

Kim Newton, Xiaoqing Sun, Vishva M. Dixit · Molecular and Cellular Biology · 2004 · 562 citations · Full text

, , +17