Mimotopes of the hyper variable region 1 of the hepatitis C virus induce cross-reactive antibodies directed against discontinuous epitopes

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

Qui‐Lim Choo, George Kuo, Amy J. Weiner et al. · Science · 1989 · 6.9K citations

Life Sciences, Genetics, Molecular Biology +13

Interferon Alfa-2b Alone or in Combination with Ribavirin as Initial Treatment for Chronic Hepatitis C

John G. McHutchison, Stuart C. Gordon, Eugene R. Schiff et al. · New England Journal of Medicine · 1998 · 3.5K citations · Full text

Pharmacy, Pharmacotherapy, Hepatic Pharmacotherapy +16

The Outcome of Acute Hepatitis C Predicted by the Evolution of the Viral Quasispecies

Patrizia Farci, Atsushi Shimoda, Alessandra Coiana et al. · Science · 2000 · 882 citations

Life Sciences, Evolutionary Biology, Infectious Diseases +17

Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV infections.

Amy J. Weiner, H. Mario Geysen, Cindy Christopherson et al. · Proceedings of the National Academy of Sciences · 1992 · 709 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein

Patrizia Farci, Atsushi Shimoda, Doris C. Wong et al. · Proceedings of the National Academy of Sciences · 1996 · 596 citations

Life Sciences, Immunology, Infectious Diseases +17