Concepedia

The Binding Energetics of First- and Second-Generation HIV-1 Protease Inhibitors: Implications for Drug Design

Adrián Velázquez‐Campoy, Yoshiaki Kiso, Ernesto Freire

Archives of Biochemistry and Biophysics · 2001 · 149 citations · 20 references

DOI

Concepts

References

20

An exact mathematical expression for describing competitive binding of two different ligands to a protein molecule

Zhixin Wang · FEBS Letters · 1995 · 374 citations

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Exact Analysis of Competition Ligand Binding by Displacement Isothermal Titration Calorimetry

Bent W. Sigurskjold · Analytical Biochemistry · 2000 · 369 citations

, , +16

Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor

Martin Markowitz, Hongmei Mo, Dale J. Kempf et al. · Journal of Virology · 1995 · 226 citations · Full text

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HIV-1 Protease Inhibitors:  Enthalpic versus Entropic Optimization of the Binding Affinity

Adrián Velázquez‐Campoy, Matthew J. Todd, Ernesto Freire · Biochemistry · 2000 · 135 citations

, , +15

Thermodynamic Basis of Resistance to HIV-1 Protease Inhibition:  Calorimetric Analysis of the V82F/I84V Active Site Resistant Mutant

Matthew J. Todd, Irene Luque, Adrián Velázquez‐Campoy et al. · Biochemistry · 2000 · 110 citations

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