Omeprazole transactivates human CYP1A1 and CYP1A2 expression through the common regulatory region containing multiple xenobiotic-responsive elements

Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450

Dominique Diaz, Isabelle Fabrev, Martine Daujat‐Chavanieu et al. · Gastroenterology · 1990 · 310 citations

Molecular Pharmacology, Biochemistry, Aryl Hydrocarbon-like Inducer +9

Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences

Masashi Iwanari, Miki Nakajima, Ryoichi Kizu et al. · Archives of Toxicology · 2002 · 162 citations

Cytochrome P450 Isoform-, Biochemistry, Cyp1b1 Mrnas +9

Identification of the human P450 enzymes involved in lansoprazole metabolism.

Robin E. Pearce, A. David Rodrigues, Jorge Goldstein et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 148 citations

Omeprazole and lansoprazole are mixed inducers of CYP1A and CYP3A in human hepatocytes in primary culture.

Rozangela Curi Pedrosa, Lydiane Pichard, Jean-Claude Ourlin et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 142 citations

Regulation of cytochrome P450 enzymes by aryl hydrocarbon receptor in human cells

Wei Li, Patricia A. Harper, Bing-Kou Tang et al. · Biochemical Pharmacology · 1998 · 131 citations

Molecular Pharmacology, Biochemistry, Human Cells +10