Tumor cells loaded with α-galactosylceramide promote therapeutic NKT-dependent anti-tumor immunity in multiple myeloma

Daratumumab, a Novel Therapeutic Human CD38 Monoclonal Antibody, Induces Killing of Multiple Myeloma and Other Hematological Tumors

Michel de Weers, Yu‐Tzu Tai, Michael S. van der Veer et al. · The Journal of Immunology · 2010 · 1K citations · Full text

Medicine, Oncology, Pharmacology +17

Activation of Natural Killer T Cells by α-Galactosylceramide Rapidly Induces the Full Maturation of Dendritic Cells In Vivo and Thereby Acts as an Adjuvant for Combined CD4 and CD8 T Cell Immunity to a Coadministered Protein

Shin‐ichiro Fujii, Kanako Shimizu, C. Smith et al. · The Journal of Experimental Medicine · 2003 · 710 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosyl-ceramide loaded mature dendritic cells in cancer patients

D. Chang, Keren Osman, John E. Connolly et al. · The Journal of Experimental Medicine · 2005 · 413 citations · Full text

Life Sciences, Immunology, Oncology +17

A Phase I Study of α-Galactosylceramide (KRN7000)–Pulsed Dendritic Cells in Patients with Advanced and Recurrent Non–Small Cell Lung Cancer

Aki Ishikawa, Shinichiro Motohashi, Eiichi Ishikawa et al. · Clinical Cancer Research · 2005 · 401 citations · Full text

Life Sciences, Immunology, Oncology +13

Differential antitumor immunity mediated by NKT cell subsets in vivo

Nadine Y. Crowe, Jonathan M. Coquet, Stuart P. Berzins et al. · The Journal of Experimental Medicine · 2005 · 383 citations · Full text

Life Sciences, Immunology, Oncology +16