Variability and functional recovery in the N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of parkinsonism in monkeys

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Richard S. Burns, Chuang C. Chiueh, Sanford P. Markey et al. · Proceedings of the National Academy of Sciences · 1983 · 2.1K citations · Full text

Medicine, Neuroscience, Pharmacology +17

Chronic parkinsonism secondary to intravenous injection of meperidine analogues

Glenn C. Davis, Adrian Williams, Sanford P. Markey et al. · Psychiatry Research · 1979 · 1.4K citations

Medicine, Neurology, Pharmacology +16

Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

J. William Langston, Lysia S. Forno, Charles S. Rebert et al. · Brain Research · 1984 · 919 citations

Medicine, Pharmacology, Toxicology +5

Permanent human parkinsonism due to 1‐methy 1–4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP)

P. Ballard, James W. Tetrud, J. William Langston · Neurology · 1985 · 626 citations

Medicine, Neurology, Pharmacology +14

Time course of nigrostriatal degeneration in parkinson's disease

Peter Riederer, St. Wuketich · Journal of Neural Transmission · 1976 · 568 citations

Life Sciences, Neurology, Neuroscience +14