Transport mechanism of anthracycline derivatives in human leukemia cell lines: uptake and efflux of pirarubicin in HL60 and pirarubicin-resistant HL60 cells

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

Susan P.C. Cole, Gabu Bhardwaj, James H. Gerlach et al. · Science · 1992 · 3.1K citations

Medicine, Molecular Biology, Oncology +16

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.

Takashi Tsuruo, Harumi Iida, Shigeru Tsukagoshi et al. · PubMed · 1981 · 1.5K citations

Medicine, Oncology, Pharmacology +7

Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance.

Rik J. Scheper, H J Broxterman, G L Scheffer et al. · PubMed · 1993 · 502 citations · Full text

Medicine, Cell Biology, Oncology +13

The MRP gene associated with a non-P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein.

PubMed · 1993 · 296 citations

Life Sciences, Biochemistry, Molecular Biology +14

Prolongation of the Circulation Time of Doxorubicin Encapsulated in Liposomes Containing a Polyethylene Glycol-Derivatized Phospholipid: Pharmacokinetic Studies in Rodents and Dogs

Alberto Gabizón, Yechezkel Barenholz, Meir Bialer · Pharmaceutical Research · 1993 · 237 citations

Pharmacy, Pharmacokinetics, Pharmacology +16