The analgesic effect of epibatidine and isomers

A METHOD FOR DETERMINING LOSS OF PAIN SENSATION

F. E. D'Amour, Donn L. Smith · Journal of Pharmacology and Experimental Therapeutics · 1941 · 3.2K citations

Nursing, Pharmacology, Pain Management +14

Epibatidine: a novel (chloropyridyl)azabicycloheptane with potent analgesic activity from an Ecuadoran poison frog

Thomas F. Spande, H. Martin Garraffo, Michael W. Edwards et al. · Journal of the American Chemical Society · 1992 · 564 citations

Medicine, Medicinal Chemistry, Pharmacology +7

A new class of indolizidine alkaloids from the poison frog, Dendrobates tricolor. X-ray analysis of 8-hydroxy-8-methyl-6-(2'-methylhexylidene)-1-azabicyclo[4.3.0]nonane

John W. Daly, Takeshi Tokuyama, T. Fujiwara et al. · Journal of the American Chemical Society · 1980 · 108 citations

Pharmacy, Chemistry, Medicinal Chemistry +10

A versatile total synthesis of epibatidine and analogs

Dao Fei Huang, T. Y. Shen · Tetrahedron Letters · 1993 · 85 citations

Pharmacy, Medicinal Chemistry, Pharmacology +7

The synthesis of (+)- and (–)-epibatidine

Stephen R. Fletcher, Raymond Baker, Mark S. Chambers et al. · Journal of the Chemical Society Chemical Communications · 1993 · 70 citations

Natural Sciences, Chemistry, Medicinal Chemistry +5