Concepedia

Synthesis and structure–activity relationship of non-phosphorus-based fructose-1,6-bisphosphatase inhibitors: 2,5-Diphenyl-1,3,4-oxadiazoles

Benren Liao, Haibing He, Lingling Yang, Lixin Gao, Liang Chang, Jie Tang, Jing-Ya Li, Jia Li, Fan Yang

European Journal of Medicinal Chemistry · 2014 · 27 citations · 38 references

DOI

Concepts

References

38

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

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Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

John C. Yoon, Pere Puigserver, Guoxun Chen et al. · Nature · 2001 · 1.8K citations

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Metabolic Effects of Metformin in Non-Insulin-Dependent Diabetes Mellitus

Michael Stümvoll, N. Nurjhan, G. Perriello et al. · New England Journal of Medicine · 1995 · 1.1K citations · Full text

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Mechanism by which metformin reduces glucose production in type 2 diabetes.

Ripudaman S. Hundal, Sylvie Dufour, Didier Laurent et al. · Diabetes · 2000 · 1.1K citations · Full text

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Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus.

Orville Kolterman, R S Gray, Justin W. Griffin et al. · Journal of Clinical Investigation · 1981 · 637 citations · Full text

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