Rat endothelin is a vasodilator in the isolated perfused mesentery of the rat

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

Masashi Yanagisawa, Hiroki Kurihara, Sadao Kimura et al. · Nature · 1988 · 10.8K citations · Full text

Life Sciences, Cell Biology, Physiology +9

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

Gilberto De Nucci, Ranjeny Thomas, Pedro D’Orléans-Juste et al. · Proceedings of the National Academy of Sciences · 1988 · 1.4K citations · Full text

Medicine, Pharmacology, Physiology +12

The effect of sympathetic nerve stimulation on vasoconstrictor responses in perfused mesenteric blood vessels of the rat

Douglas D. McGregor · The Journal of Physiology · 1965 · 641 citations · Full text

Life Sciences, Physiology, Neurophysiology +13

Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide.

Masashi Yanagisawa, Akihiro Inoue, Tomohisa Ishikawa et al. · Proceedings of the National Academy of Sciences · 1988 · 547 citations · Full text

Medicine, Pharmacology, Physiology +13