Concepedia

Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure

Anastasios Lymperopoulos, Giuseppe Rengo, Hajime Funakoshi, Andrea D. Eckhart, Walter J. Koch

Nature Medicine · 2007 · 234 citations · 30 references

Concepts

Life SciencesCardiologyPhysiologyNeuroendocrinologyPathophysiologySignal TransductionAdrenal HormonesAutonomic Nervous SystemCardiovascular DiseaseCardiovascular Molecular PhysiologyHeart FailureCardiovascular Autonomic ControlHeart Failure Molecular MechanismsHeart Failure PhysiologySympathetic ActivationSympathetic Cardiac ControlSympathetic Nervous System PhysiologySympathetic Nervous System Responses

References

30

The Pharmacological Basis of Therapeutics

American Journal of Health-System Pharmacy · 1976 · 8.2K citations

Medicine, Pharmacology, Pharmacotherapy +10

Plasma Norepinephrine as a Guide to Prognosis in Patients with Chronic Congestive Heart Failure

Jay N. Cohn, T. Barry Levine, Maria Teresa Olivari et al. · New England Journal of Medicine · 1984 · 3.1K citations

Medicine, Cardiology, Clinical Cardiology +9

Williams Textbook of Endocrinology

S. S. Stoffer · JAMA · 1999 · 1.3K citations

Medicine, Endocrinology, Physiology +8

Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor

Walter J. Koch, Howard A. Rockman, Philippe Samama et al. · Science · 1995 · 715 citations

Medicine, Cardiology, Pharmacology +17

Synergistic Polymorphisms of β<sub>1</sub>- and α<sub>2C</sub>-Adrenergic Receptors and the Risk of Congestive Heart Failure

Kersten M. Small, Lynne E. Wagoner, Albert M. Levin et al. · New England Journal of Medicine · 2002 · 530 citations

Medicine, Cardiology, Molecular Genetics +17