Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

Gillian L. Dalgliesh, Kyle Furge, Chris Greenman, +48

Nature

ChromatinCancer ResearchUrologyHistone Modifying GenesGenitourinary Cancer +9

The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals

Nailing Zhang, Haibo Bai, Karen K David, +7

Developmental Cell

Tumor BiologySignal TransductionYap OncoproteinSignaling PathwayMedicine +7

Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas

Martin Ruttledge, Julie Sarrazin, Shyam Rangaratnam, +9

Nature Genetics

Developmental BiologyNf2 GeneMendelian DisorderComplete InactivationGenetics +4

PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas

Jong Woo Lee, Young Hwa Soung, Su Young Kim, +7

Oncogene

MedicinePik3ca GenePathologyHepatocellular CarcinomasCancer Genomics +8

High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas.

A. Bianchi, Shin‐ichiro Mitsunaga, J Q Cheng, +6

Proceedings of the National Academy of Sciences

Primary Malignant MesotheliomasMalignant MesotheliomasTumoral PathologyGliomaMm Cell Lines +9

Contact-dependent inhibition of EGFR signaling by Nf2/Merlin

Marcello Curto, Banumathi K. Cole, Dominique Lallemand, +2

The Journal of Cell Biology

The Nf2 Tumor Suppressor, Merlin, Functions in Rac-Dependent Signaling

Reuben J. Shaw, J. Guillermo Paez, Marcello Curto, +9

Developmental Cell

Signaling PathwayMedicineNf2 Tumor SuppressorTumor SuppressorCancer Biology +3

<i>Nf2</i> /Merlin controls progenitor homeostasis and tumorigenesis in the liver

Samira Benhamouche, Marcello Curto, Ichiko Saotome, +4

Genes & Development

Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer

Sug Hyung Lee, Min Sun Shin, Won Sang Park, +10

Oncogene

MedicinePathologyCell DeathBronchial NeoplasmCancer Genomics +8

Mutations in transcript isoforms of the neurofibromatosis 2 gene in multiple human tumour types

A. Bianchi, Tetsuo Hara, Vijaya Ramesh, +8

Nature Genetics

Neuro-oncologySomatic VariantTumor HeterogeneityTranscript IsoformsPathology +7