Concepedia

The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals

Nailing Zhang, Haibo Bai, Karen K David, Jixin Dong, Yonggang Zheng, Jing Cai, Marco Giovannini, Pentao Liu, Robert A. Anders, Duojia Pan

Developmental Cell · 2010 · 817 citations · 58 references

DOIFull text

Open access

Concepts

References

58

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Bin Zhao, Xiaomu Wei, Weiquan Li et al. · Genes & Development · 2007 · 3.2K citations · Full text

, , +17

Elucidation of a Universal Size-Control Mechanism in Drosophila and Mammals

Jixin Dong, Georg Feldmann, Jianbin Huang et al. · Cell · 2007 · 2.4K citations · Full text

, , +9

The Hippo Signaling Pathway Coordinately Regulates Cell Proliferation and Apoptosis by Inactivating Yorkie, the Drosophila Homolog of YAP

Jianbin Huang, Shian Wu, Jose Barrera et al. · Cell · 2005 · 1.9K citations · Full text

, , +12

YAP1 Increases Organ Size and Expands Undifferentiated Progenitor Cells

Fernando D. Camargo, Sumita Gokhale, Jonathan B. Johnnidis et al. · Current Biology · 2007 · 1.3K citations · Full text

, , +14

hippo Encodes a Ste-20 Family Protein Kinase that Restricts Cell Proliferation and Promotes Apoptosis in Conjunction with salvador and warts

Shian Wu, Jianbin Huang, Jixin Dong et al. · Cell · 2003 · 1.1K citations · Full text

, , +16