The Notch signaling pathway in the cnidarian Hydra

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

Eric H. Schroeter, Jeffrey A. Kisslinger, Raphael Kopan · Nature · 1998 · 1.6K citations

Signal Transduction, Signaling Pathway, Cell Interaction +6

A Novel Proteolytic Cleavage Involved in Notch Signaling

Christel Brou, Frédérique Logeat, Neetu Gupta et al. · Molecular Cell · 2000 · 1.1K citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +6

Functional gamma‐secretase inhibitors reduce beta‐amyloid peptide levels in brain

Harry F. Dovey, Varghese John, J. P. Anderson et al. · Journal of Neurochemistry · 2001 · 877 citations · Full text

Protein Secretion, Neurochemical Biomarkers, Amyloid Precursor Protein +17

A Ligand-Induced Extracellular Cleavage Regulates γ-Secretase-like Proteolytic Activation of Notch1

Jeff S. Mumm, Eric H. Schroeter, Meera Saxena et al. · Molecular Cell · 2000 · 853 citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +10

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

Annapoorni Rangarajan · The EMBO Journal · 2001 · 852 citations · Full text

Skin Development, Developmental Biology, Cell Division +11