Concepedia

Saikosaponin d protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling

Aiming Liu, Naoki Tanaka, Lu Sun, Bin Guo, Jung Hwan Kim, Kristopher W. Krausz, Zhong‐Ze Fang, Changtao Jiang, Julin Yang, Frank J. Gonzalez

Chemico-Biological Interactions · 2014 · 81 citations · 28 references

DOI

Concepts

References

28

IKKβ Couples Hepatocyte Death to Cytokine-Driven Compensatory Proliferation that Promotes Chemical Hepatocarcinogenesis

Shin Maeda, Hideaki Kamata, Jun‐Li Luo et al. · Cell · 2005 · 1.2K citations · Full text

, , +16

Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2

Judy L. Raucy, Jerome M. Lasker, Charles S. Lieber et al. · Archives of Biochemistry and Biophysics · 1989 · 483 citations

, , +14

Protective Role of Kupffer Cells in Acetaminophen-Induced Hepatic Injury in Mice

Cynthia Ju, Timothy P. Reilly, Mohammed Bourdi et al. · Chemical Research in Toxicology · 2002 · 356 citations

, , +17

Protection against Acetaminophen Toxicity in CYP1A2 and CYP2E1 Double-Null Mice

Hani Zaher, Jeroen Buters, Jerrold M. Ward et al. · Toxicology and Applied Pharmacology · 1998 · 322 citations

, , +9

Protection against acetaminophen-induced liver injury and lethality by interleukin 10: Role of inducible nitric oxide synthase

Mohammed Bourdi, Yasuhiro Masubuchi, Timothy P. Reilly et al. · Hepatology · 2002 · 301 citations

, , +14