DNAzyme‐Like Activity of Hemin–Telomeric G‐Quadruplexes for the Optical Analysis of Telomerase and its Inhibitors

Abstract

An escape from the TRAP: Telomere chains self-assemble into catalytically active hemin–G-quadruplex units. We describe how the resulting DNAzyme units can be used for quantitative analysis of telomerase activity and its inhibitors. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.