Concepedia

Quantitative modeling of selective lysosomal targeting for drug design

Stefan Trapp, Gus R. Rosania, Richard W. Horobin, Johannes Kornhuber

European Biophysics Journal · 2008 · 153 citations · 27 references

DOIFull text

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Concepts

References

27

The effect of sodium ions on the electrical activity of the giant axon of the squid

A. L. Hodgkin, B. Katz · The Journal of Physiology · 1949 · 3.5K citations

, , +13

POTENTIAL, IMPEDANCE, AND RECTIFICATION IN MEMBRANES

David E. Goldman · The Journal of General Physiology · 1943 · 2.8K citations · Full text

, , +14

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

S Ohkuma, Brian D. Poole · Proceedings of the National Academy of Sciences · 1978 · 2.2K citations · Full text

, , +17

Physiologically Based Pharmacokinetic Modeling 1: Predicting the Tissue Distribution of Moderate-to-Strong Bases

Trudy Rodgers, David E. Leahy, Malcolm Rowland · Journal of Pharmaceutical Sciences · 2005 · 774 citations

, , +13

Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages.

Brian D. Poole, S Ohkuma · The Journal of Cell Biology · 1981 · 754 citations · Full text

, , +15