Concepedia

Synthesis and molecular modeling of some novel hexahydroindazole derivatives as potent monoamine oxidase inhibitors

Nesrin Gökhan-Kelekçi, Ömer Şimşek, Ayşe Ercan, Kemal Yelekçi, Zarife Sibel Şahin, Ş. Işık, Gülberk Uçar, A. Altan Bilgin

Bioorganic & Medicinal Chemistry · 2009 · 38 citations · 41 references

Open access

Concepts

PharmacyMedicinal ChemistryPharmacologyDrug DiscoveryMolecular PharmacologyStructure-activity RelationshipsEnzyme InhibitionLead Compound DesignLigand-based DesignMolecular ModelingPotency OptimizationStructure-activity Relationship AnalysisChemical Synthesis Of AnaloguesMechanism-based Drug DesignMedicinal Chemistry ApplicationsMonoamine Oxidase InhibitionMonoamine Oxidase InhibitorsMonoamine Oxidase InvolvementStructure-activity Relationship Modeling

References

41

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

Mark A. Bradford · Analytical Biochemistry · 1976 · 225.4K citations

Life Sciences, Biochemistry, Protein Biochemistry +7

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Marion M. Bradford · Analytical Biochemistry · 1976 · 211.2K citations

Life Sciences, Biochemistry, Protein Biochemistry +7

VMD: Visual molecular dynamics

William Humphrey, Andrew Dalke, Klaus Schulten · Journal of Molecular Graphics · 1996 · 66.6K citations

Natural Sciences, Biophysics, Physics +12

Comparison of simple potential functions for simulating liquid water

William L. Jorgensen, Jayaraman Chandrasekhar, Jeffry D. Madura et al. · The Journal of Chemical Physics · 1983 · 42.1K citations

Natural Sciences, Chemistry, Physics +17

<i>ORTEP</i>-3 for Windows - a version of<i>ORTEP</i>-III with a Graphical User Interface (GUI)

Louis J. Farrugia · Journal of Applied Crystallography · 1997 · 19.9K citations

Natural Sciences, Computer Science, Computational Chemistry +16